Fig. 1. Dally and Dlp are required for the proper distribution of extracellular Wg. All wing discs are oriented dorsal top-right, anterior top-left. All mutant clones are marked by the absence of GFP and outlined by broken lines. (A-C') Extracellular Wg staining in discs bearing large clones mutant for dally. Extracellular Wg is significantly reduced in the clones in a cell non-autonomous manner. The yellow arrows indicate the wild-type cells that have reduced extracellular Wg level. (D-E') Extracellular Wg staining in discs bearing large clones mutant for dlp. Within the clones, extracellular Wg is reduced outside of a zone that is 7-10 cell diameters wide and centered at the DV boundary. (F-G') Extracellular Wg staining in discs bearing large clones mutant for both dally and dlp. Extracellular Wg level is greatly reduced in these clones, and the reduction is stronger than that of dally or dlp alone.