Fig. 5. Accumulated Wg in fz-fz2 or arr clones are mainly resulted from upregulated Dlp. Extracellular Wg staining in wing discs carrying mutant clones of varying genotypes. Discs are oriented dorsal right, anterior up (A-D'), and dorsal top-right, anterior top-left (E-F'). The mutant clones are marked by the absence of GFP and outlined by broken lines except in C,C'. In F,F', only the clone far away from DV boundary is outlined. (A,A') A wing disc carrying clones mutant for fz-fz2. Dlp levels are enhanced in these clones. (B,B') A wing disc carrying clones mutant for sfl-fz-fz2. Extracellular Wg levels are reduced in the clones. (C,C') A wing disc carrying clones mutant for arr. Dlp levels are enhanced in the clones. (D,D') A wing disc carrying clones mutant for botv-arr. Extracellular Wg is reduced in the clones. (E-F') Wing discs carrying clones mutant for dsh. Extracellular Wg levels are increased in the clones. This effect can be clearly seen even the clones are located far away from Wg-expressing cells. Some of the mutant cells are located more than 20 cells away from the DV boundary.