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Fig. 6. A model for Wingless specification of Slouch clusters I and II. An illustration of the two-step process by which Wg specifies Slouch cI and cII in the developing mesoderm. Wg provides two contributions for Slouch cII: one through Twist and a second that is Twist independent. The Twist-independent Slouch activation is likely to involve transcriptional regulation by the Wg transcriptional effector Pangolin/Tcf. cI needs Wg only to generate a myogenic competency domain through Twist.