Fig. 9. A schematic representation of OB structures in wild-type and
Arx-deficient mice at P0. Diagrams show horizontal sections of the
olfactory bulb (OB) in wild-type (A) and Arx-deficient mice (B).
Anterior is to the top and lateral is to the left. Mutant mice showed the
impaired entry of interneuron progenitors (orange) into the OB, the loss of
TH(+) periglomerular cells (dark pink), and the disorganization of OB layer
structure. The innervation of olfactory axons (purple) and the apical
projection of radial glial fibers (blue) were observed only at the
rostromedial side of OB in mutant mice. The olfactory axons that failed to
reach mutant OB formed the fibrocellular mass (FCM) in front of the OB. RMS,
rostral migratory stream.