Fig. 4. Molecular lesions in pfs2 alleles and alignment of PFS2 with similar proteins. (A) In the pfs2-1 allele, the T-DNA inserted into the third intron, whereas in pfs2-2 the T-DNA inserted into the second intron. The homeodomain region is encoded by the second exon. (B) Protein alignment is shown for PFS2, PFS2-LIKE, WUS and PRS. Within the homeodomain region (amino acids 59-122), these proteins share 95% amino acid identity. Other conserved regions are similarly boxed. Outside these regions, the homology drops markedly. Conserved amino acids are denoted with a dot, while identical amino acids are marked with an asterisk.