Fig. 7. Radial intercalation in heterozygous and recessive hab mutants.
Selected frames from time-lapse video recordings of the lateral epiblast at
about 80% epiboly using Nomarski DIC optics. Cells are pseudo-colored by layer
and individual cells are identified by numbers. In both ZMD heterozygous (A)
and homozygous hab mutants (B), cells from the interior layer of the
epiblast (blue) intercalate in among cohorts of cells of the exterior layer
(green). (C) In homozygous hab mutants, cells frequently leave the
exterior layer. Three exterior cells (green with negative numbers),
sequentially move to the interior layer of the epiblast (color shift to blue),
and disappear under the neighboring exterior layer cells.