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Fig. 1. (A) Schematic drawing of a mouse embryo at E11. Yolk sac (YS), head, somites, limb buds (Lb), heart (H), liver (L), umbilical (U) and vitelline (V) arteries, and the aorta-gonad-mesonephros (AGM) region were dissected and cells isolated for further testing. (B) AGM region, divided into the aorta (A), with the adjacent mesenchyme (M), and the gonads and mesonephros (GM) that constitute the urogenital ridges.