Fig. 7. BMP suppresses Edar but not Eda. (A) An embryo infected
with a virus that encodes BMP4 shows suppression of Edar in the
feather tract where bud formation is suppressed (black arrows), and no effect
ahead of the morphogenetic wave or in the pseudoapteria (red arrows). (B)
Detection of viral transcripts reveals infection in the areas where bud
formation is suppressed (black arrows), as well as in the lateral regions of
the flank (red arrows). (C) An infected embryo shows maintenance of the
diffuse expression of Eda in an area of suppressed bud formation that
would normally exhibit the honeycomb pattern of expression at this stage
(black arrow). No alteration of Eda expression is observed ahead of
the morphogenetic wave or in the pseudoapteria (red arrows). (D) Subsequent
detection of viral transcripts demonstrates infection in the areas of bud
suppression (black arrow), as well as in the lateral regions indicated in C
(red arrows).