Fig. 7. Ncad isoforms mediate promiscuous heterophilic interactions. S2 cells expressing different cadherins and GFP or Ds-red marker are assessed for their ability to induce cell aggregations. (A-D) Cross-adhesion between cells expressing different Ncad isoforms or E-cadherin. Two S2 cell populations expressing different cadherins are separately labeled with GFP (green) or Ds-red (red) and mixed to form aggregates. (A) E-cadherin and Ncad 7b-13a-18b-expressing S2 cells segregate into two types of clusters. (B-D) S2 cells expressing different Ncad isoforms (as indicated) coaggregated to form mixed cell clusters. (E) A table summarizing the cross-adhesion results. +: intermixed; -: segregated.