Fig. 1. (A) Antisense oligonucleotides to KGFR/Bek decrease branching morphogenesis
of E12 SMGs; a representative photograph of each group is shown. (B) The
number of terminal buds of at least six glands at each timepoint was counted.
There was a significant decrease (ANOVA, **P<0.01) in
the number of buds in the antisense-treated glands. (C) Antisense
oligonucleotides decrease FGFR2 expression by
50%; the
expression of FGFR2 was normalized to GAPH.