Fig. 4. Distinct profiles of ß-catenin localization associated with distinct profiles of Myc and cyclin D1. (A)ß-Catenin immunostaining of jejunum sections from control and mutant mice (D4), shown at low and high magnification. (B, left) Levels of Myc and cyclin D1 transcripts in the jejunums of control and mutant mice on day 4, as measured by RT-PCR. The level of each transcript is expressed relative to that in wild-type mice. (B, right) Western blot analysis of ß-catenin, Myc and Cyclin D1 in the jejunums of control and mutant mice on day 4. (C) Myc (a,c) and Cyclin D1 (b,d) staining in sections of jejunum from control (a,b) and mutant mice (c,d) on day 4. Similar staining patterns were observed all along the small intestine.