Fig. 10. KIS-L is required for the association of Pol IIo^ser2 with polytene chromosomes. The distribution of KIS-L (red; A,D,G,J), Pol IIa (green; B,E,H,K), Pol IIo^ser5 (blue; C,F) and Pol IIo^ser2 (blue; I.L) on chromosomes isolated from wild type (A-C,G-I) and kis^k13416 mutant larvae (D-F,J-L) is shown. The levels of both Pol IIa and Pol IIo^ser5 are unaffected by the loss of KIS-L. By contrast, loss of KIS-L results in a dramatic reduction in the level of Pol IIo^ser2 associated with chromosomes.