Fig. 7. Models of the functional differentiation of TGN in vesicle trafficking pathways. The TGN does not have a uniform function but is functionally differentiated into subpopulations that are specialized to transport to the plasma membranes (yellow), to endosomes (blue), or to prevacuolar compartments (PVC) (white). VAN3 is located in a subpopulation of the TGN that may be involved in the transport of auxin signaling modules and/or secreted vascular formation factors.