Fig. 9. The origins of oligodendrocytes in the embryonic rodent spinal cord. From
E12.5 in the mouse, OLPs are generated from pMN in the ventral VZ. Later, from
approximately E16, a subsidiary population emerges from radial glial cells in
the Dbx1-expressing domain that spans the dorsoventral midline. The latter
population contributes around 5% of all oligodendrocyte lineage cells in the
postnatal cord. Our data do not rule out the possibility that there are
additional minor sources of oligodendrocytes outside either pMN or the Dbx
domain.