Fig. 1. Predicted structure and sequence analysis of Oncopeltus even-skipped. (A) Cartoon of predicted Of'eve protein structure with conserved N-terminal domain (N), homeodomain (HD) and C-terminal domain (C). Underlined are the regions used for synthesizing dsRNA and in situ probes. The 3' fragment is approximately 600 bp long and spans a small region of the homeodomain. The 5' fragment is approximately 260 bp long and does not include any of the homeodomain. (B) Conserved N-terminal domain of even-skipped from Drosophila melanogaster, Tribolium castaneum, Oncopeltus fasciatus and Schistocerca americana. (C) Conserved C-terminal domain from the same insect species. The Groucho co-repressor interaction domain is underlined. (D) Conserved homeodomain region from the four insect species.