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Fig. 2. Cultured Cdx2-/- embryos fail to form an expanded blastocyst. Bright-field images of Cdx2+/+ embryos (A-D) and Cdx2-/- embryos (E-I). Eight-cell embryos from Cdx2+/– intercrosses were individually cultured, monitored for 72 hours, and images recorded at (A,E) 6 hours; (B,F) 24 hours; (G) 30 hours; (C,H) 48 hours; and (D,I) 72 hours. Scale bars: 25 µm.