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Figure 7


Fig. 7. An illustration of {alpha}8 connexin (Cx50) protein topology. Known human mutations are indicated by green squares (R23T, E48K, P88S, I247M) and an orange oval (V64G) (Shiels et al., 1998; Berry et al., 1999; Polyakov et al., 2001; Willoughby et al., 2003; Zheng et al., 2005), and known mouse mutations are indicated by red circles (G22R, D47A, and S50P) and an orange oval (V64A) (Chang et al., 2002; Graw et al., 2001; Steele et al., 1998). An arrow indicates the S50P mutation.