Development -- Hashimoto et al. 133 (11): 2201 Figure IG3

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Fig. 3. Influence of VEGF on retinal ganglion cell differentiation. (A) Effects of VEGF concentrations on development of NF⁺ cells in E5-E7 explants in vitro (n=5). (B) Effects of sFLK1- and VEGF-producing cells on percentages of NF⁺ cells in vivo at E5. Black and white bars represent implanted and the contralateral non-implanted eyes, respectively (n=6; *P<0.03). (C-E) Immunostaining show effects of AP (C), sFLK1 (D) or VEGF (E) on Islet1/2⁺ cells in E5-E7 explants. Scale bars: 50 µm.