Fig. 3. Inhibition of spore induction. (A) KP cells developing as monolayers were treated with various concentrations of GABA and glutamate, and the proportion of spores determined after 1 hour: 1 nM GABA (black circles), 10 nM GABA (triangles), 100 nM GABA (squares), 1 µM GABA (white circles). Glutamate was added simultaneously with GABA at the concentrations indicated. (B) SDF-2 was added to the cells at 0.1 pM (circles); 10 pM SDF-2 (triangles); 10 nM (squares). Glutamate was added simultaneously at the concentrations indicated. (C) GABA and CGP 55845 were added at various concentrations and the proportion of spores determined after 1 hour; 1 nM GABA (black circles), 10 nM GABA (triangles), 100 nM GABA (squares), 1 µM GABA (white circles). CGP 55845 was added simultaneously at the concentrations indicated. (D) SDF-2 was added to the cells at 0.1 pM (circles); 10 pM SDF-2 (triangles); 10 nM (squares). CGP 55845 was added simultaneously at the concentrations indicated.