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Figure 7


Fig. 7. hrT morphants have defects in cloaca development. (A,B) Compared with mismatch (mm) control morphants (A), hrT morphant embryos (B) develop dysmorphic cloacas. Embryos were photographed at 48 hpf. Arrow indicates the region where the cloacal opening normally develops. (C-H) Expression of (C,D) tbx2b, (E,F) hoxd13 and (G,H) gata3 in mismatch control morphants (C,E,G) and hrT morphants (D,F,H) at 18 hpf (C-F) or 20 hpf (G,H). Note the normal expression of these three genes in hrT morphant embryos. Arrowheads mark the proctodeal region in C-H.