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Figure 1


Fig. 1. Human and fly APC1 and APC2. (A-C) There are nine mutant alleles of fly APC2: five point mutants in the Arm repeat region (black arrows) and four truncations (blue arrows). We used a null allele of APC1 (APC1Q8) resulting from a nonsense mutation in Arm repeat 4 (Ahmed et al., 1998).