Fig. 5. The fate map of second-segment skeletal derivatives is altered in
moz mutants. Summaries of wild-type (A-C) and
moz- (D-F) fatemaps and representative
examples (G-R). Lateral views (A,D,G,J,M,P) and dorsal
cross-sectional views at the level of the labelled cell with anterior to the
left and lateral up (B,E,H,K,N,Q) are shown at 24 hpf. The facial skeleton is
shown at 4 dpf (C,F,I,L,O,R). Filled circles denote facial cartilage
precursors, and open circles denote precursors of neurocranial cartilage that
surrounds the otic capsule. Triangles and squares denote precursors of the Op
(upper) and Br (lower) dermal bones, respectively. moz-
CNC that made no skeleton are hatched squares. In B and E, areas of surface
ectoderm (blue), endoderm (pink), and stomodeal ectoderm (grey) are shown
(compare to insets in Fig.
3A,D). In A,B,G,H, first pouch endoderm (P) is labelled. Wild-type
examples of anterior Hm cartilage (G-I) and Op osteocyte (J-L) precursors are
shown. (M-R) moz- CNC in similar positions fail to make
skeleton. Note that in both wild types and moz mutants the most
dorsal CNC in the first and second segment contribute to neurocranial
cartilage that surrounds the otic capsule. Scale bars: 50 µm.