Fig. 7. XHRT1 reverses the effect of Su(H)DBM on Evi1 but is not sufficient to restore XSMP-30 expression. (A-H) Late tailbud/early tadpole stage embryos injected with 500 pg of Su(H)DBM mRNA together with 500 pg of XHRT1a-mut-MT-hGR mRNA, untreated (A-D) or dexamethasone treated (E-H) at stage 22. ß-galactosidase RNA was co-injected to identify the injected side. Note the decrease of XSMP-30 and the increase of Evi1 expression in untreated embryos, and the reduction of both XSMP-30 and Evi1 expression in treated embryos. (I) Quantification of the results. Embryos were classified into two phenotypes (increase Evi1 and decrease XSMP-30). n, number of cases analysed.