Fig. 8. DFer interactions with the JNK pathway. (A) Stage 13 wild-type embryos express dpp in leading edge cells (arrowhead) and in the midgut. (B,C) In Src42A^myri embryos (B), dpp expression in leading edge cells (arrowheads) is slightly reduced and expression is almost lost in Src42A^myri;dfer¹ double mutants (C). (D-G) dpp (E) and puc-lacZ (G) expression in leading edge cells of dfer^gof mutants (arrowheads) is comparable to wild type (D,F). (H,I) Phosphotyrosine staining in dfer^gof/dfer^gof (H) and UAS-puc, dfer^gof/dfer^gof (I) embryos. (I) Expression of the JNK inhibitor Puc with dfer^gof serving as the GAL4 driver, rescues the dorsal open phenotype of dfer^gof mutants.