Fig. 3. Neurogenesis in wild-type and laminin
1III4-/-
cortex. (A-H) E14 or E18 wild-type and laminin
1III4-/- cortex sections stained for the neuronal antigen
ßIII-Tubulin or Math2 mRNA. Arrowheads in B and red arrows in H indicate
neuronal ectopias in the subarachnoidal space, arrows in B indicate ectopic
clusters of precursors in the laminin
1III4-/- cortex. The
broken yellow and red lines in C delineate the cortical plate thickness in
relation to the cortex thickness. Math2 expression is absent in the upper
layers of the laminin
1III4-/- cortex (H), while these
neurons still contain ßIII-Tubulin (F). Scale bars: 100 µm for
A,B,E,F; 200 µm for C,D,G,H.