Fig. 7. FGF signaling is required for induction of chordin by
ß-catenin, Squint and Bozozok. chd and bmp4
expression in ichabod embryos (A,B) is restored to
wild-type pattern by injection of ß-catenin RNA (C,F),
sqt RNA (I,L), or boz RNA (O,R).
Co-injection of XFD RNA inhibits induction of chd by ß-catenin
(D), Sqt (J) and Boz (P), and dorsal repression of
bmp4 by ß-catenin (G) and Sqt (M). However,
repression of dorsal expression of bmp4 by Boz is observed in XFD
RNA-injected embryos (S, compared with R and B). Co-injection with d50
RNA had no effect on ß-catenin, Sqt, or Boz functions
(E,H,K,N,Q,T). Embryos are at 70%
epiboly, shown in lateral view, dorsal to the right.