Fig. 6. RhoA affects DE-cad function in rotation and localization.
(A,B) Tangential sections of adult eyes of the following
genotypes (anterior is leftwards and dorsal upwards). (A) Co-expression of
sev>DEcadDN with UAS-GFP (control). (B) Co-expression of
sev>DEcadDN with UAS-RhoAIR.
UAS-RhoAIR enhances under-rotation associated
with sev>DEcadDN (compare A with B). Arrows are as in
Fig. 1. (C) Confocal
microscopy image of DE-cad (magenta and C') localization in
rhoA72R clones (hypomorphic allele). DE-cad distribution within
nascent ommatidial preclusters is disorganized, the overall DE-cad levels are
reduced posterior to MF. Green: GFP labeling wild-type tissue.