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Figure 6


Fig. 6. PAR-6 protein does not accumulate at the cortex in cdc-37(RNAi); cdc-42(RNAi) embryos. (A,C) GFP::PAR-6 embryo treated with cdc-42(RNAi). (A) Punctate GFP::PAR-6 becomes somewhat asymmetric early in the cell cycle. (C) At metaphase, GFP::PAR-6 becomes undetectable at the cortex. (B,D) GFP::PAR-6 embryos treated with cdc-37(RNAi); cdc-42(RNAi). GFP::PAR-6 does not become cortical at any stage in the cell cycle. Control uninjected or cdc-37(RNAi) embryos treated on the same day looked the same as embryos in Fig. 4, columns 3 and 4, respectively.