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Figure 4


Fig. 4. Vascular defects in Man1{Delta}/{Delta} embryos. Gross morphology of the yolk sac (A,B) and embryo proper (E-G) of wild-type and Man1{Delta}/{Delta} embryos at E10.0. (C,D) Histological analysis of E10.0 yolk sac of wild-type and Man1{Delta}/{Delta} embryos. (G) Arrow indicates clumps of blood cells; white arrowhead indicates an enlarged pericardium. Scale bars: 400 µm in A,B,E-G; 100 µm in C,D.