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Fig. 5. Molecular analysis of forebrain development in Raldh2-/- embryos. Whole-mount in situ hybridization of Foxg1 (A,B: 13-14 somites; C,D: E9.5), Emx2 (E,F:11-12 somites; G,H: E9.5), Nkx2.1 (I,J: 11-12 somites; K,L: E9.5), Delta1 (M,N: 13-14 somites) and Hes5 (O,P: 15-16 somites). Embryo genotypes are indicated above. Main panels are profile views, except in C,G,H (frontal views) and D,K,L (ventral views of the forebrain). Insets show profile views of the same embryos (C,D,G,H,K,L), or additional embryos at the 14- to 15-somite stage (E,F,I,J) or E9.5 (M,N). di, diencephalon; hb, hindbrain; mb, midbrain; te, telencephalon.