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Figure 1


Fig. 1. C. elegans Pax2/5/8 mutants have increased germline cell apoptosis. (A-H) Nomarski DIC (A,C,E,G) and epifluorescence (B,D,F,H) images of the gonad of adult hermaphrodite animals, stained with SYTO12, which preferentially labels dying germ cell nuclei (Gumienny et al., 1999). Arrowheads indicate dying cells or clusters of dying cells. (A,B) Wild type. (C,D) egl-38(n578). (E,F) pax-2(ok935). (G,H) pax-2(ok935) egl-38(n578). (I) Average number of cell corpses per gonad arm for wild type and Pax2/5/8 mutants. Error bars represent s.e.m. for at least 20 animals in each category. (J) Average number of cell corpses per gonad arm for different egl-38 mutants. Data presented as in I.