Fig. 6. Ubx repression of dally restricts the extent of Dpp
activity in the haltere disc. (A) dally
(dally-lacZ) expression in the wing disc, showing stronger signal in
the dorsal-ventral and A/P boundaries (arrow) and in the lateral regions.
(B) In the haltere disc, dally is not transcribed in AB cells
and the signal in the dorsal-ventral boundary is restricted to the anterior
compartment. There is also lower signal throughout the pouch. (C) An
omb-gal4; Df109 UAS-dsRNA>Ubx/+ haltere disc,
showing a dally pattern similar to that of the wing disc. The arrow
marks the A/P stripe. (D,D') Ubx-expressing
clones in the wing disc, marked by the GFP expression (D, in green), eliminate
dally signal (D,D', in red; arrows). (E) The expression of
dally under the control of the ap-Gal4 line extends the
P-Mad signal in the dorsal domain (d, arrows), where the line drives
expression; v, ventral region. (F) The ectopic expression of activated
Tkv in the dorsal (d) domain of the wing pouch (MS1096-Gal4 driver)
downregulates mtv transcription; v, ventral region.
(G,H) In the dorsal haltere pouch of MS1096;
UAS-tkvDN/+ larvae, the expression of a
dominant-negative form of Tkv does not activate mtv (G) or
dally (H) expression at the A/P boundary.