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Figure 2


Fig. 2. The targeted tTA transactivator is expressed in an equivalent spatial pattern to endogenous Hand1. Whole-mount RNA in situ hybridisation analysis of Hand1 (A) and tTA (B) in control embryos at E9.5. (C,D) Frontal sections through the distal OFT region. (E-H) Sagittal sections through the first branchial arch (E,F) and heart (G.H). as, aortic sac; ba, branchial arch; oft, outflow tract; lv, left ventricle. Scale bars: in B, 200 µm for A,B; in H, 50 µm for C-H.