Fig. 3. Canonical Wg signaling pathway affects the L-mutant phenotype. (A-D') Increasing levels of canonical Wg signaling in the eye by overexpressing Wg (A) or Arm (C) results in small eyes. However, in the L²/+-mutant background, overexpression of Wg (B,B') or Arm (D,D') results in the enhancement of loss-of-ventral-eye to a no-eye phenotype. (E-H') Reducing Wg signaling by overexpressing Sgg (E) or dTCF^DN (G) in wild-type eye does not affect eye size. However, in the L²/+ background, overexpression of Sgg (F,F') or dTCF^DN (H,H') strongly suppresses the loss-of-ventral-eye phenotype to near that of wild-type eye. Dashed line marks the lost boundary of the eye field. AN, antenna.