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Figure 1


Fig. 1. BE in humans and p63-/- mice. (A) BE with separation of pubic bones and genitalia in a female. (B) Covered BE in a male. (C) The wild-type E18.5 embryo (10x). (D) BE in an E18.5 p63-/- embryo (10x). (E,F) Hematoxylin and Eosin staining of sagittal sections of wild-type (E) and p63-/- (F) E18.5 embryos (40x). White arrow: umbilical hernia. (G,H) Hematoxylin and Eosin staining of transverse sections of E18.5 wild-type (G) and p63-/- (H) embryo pelvises (40x). (Image A,B courtesy of J. L. Salle, Hospital for Sick Children, Toronto, Canada).