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Figure 7


Fig. 7. Epithelial-mesenchymal interactions. (A,B) Msx1 expressions (immunohistochemistry) in transverse sections of E14.5 wild-type (A) and p63-/- (B) bladders (100x). (C,D) Fgf8 in situ hybridization in the sagittal sections of E11.5 wild-type (C) and p63-/- (D) UGS (100x). (E,F) m-snail in situ hybridization of E14.5 wild-type (E) and p63-/- (F) bladders (sagittal sections) (100x). (G,H) BrdU incorporation in the sagittal sections of wild-type (G) and p63-/- (H) E11.5 UGS (100x). Arrows in A-H represent the ventral UGS. (I) Histogram of cell proliferation in both epithelium and mesenchyme of E11.5 wild-type and p63-/- UGS.