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Figure 4


Fig. 4. Normal Hox gene expression in E8.5 eed mutant embryos. Representative flat-mount images of wild-type (A,C) and l7Rn51989SB/1989SB mutant embryos (B,D) following mRNA in situ hybridization with Hoxa5 (A,B) and Hoxb6 (C,D) antisense cRNA probes. Note that wild-type and l7Rn51989SB/1989SB mutant embryos present the same anterior Hox gene expression boundaries in somites (s). Arrows denote the first somite and the anterior Hox gene expression boundary. All images were captured at 50x magnification.