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Fig. 8. Ras-dva downregulation, in contrast to Ras, is unable to interrupt FGF signaling in the posterior regions of the embryo. (A,A') Microinjection of DN-RasS17N results in inhibition of the mesoderm marker Brachyury (Bra) around the blastopore at the midgastrula stage (black arrowheads). (B,B') By contrast, DN-Ras-dvaT22N has no influence upon Bra expression.