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Fig. 3. Expression of Fz5/8 during perturbed development. (A) Fz5/8 expression in animalized embryos obtained either by treatment with 0.1 mM zinc chloride or by overexpression of the wild-type form of GSK3ß. (B) Fz5/8 expression in embryos vegetalized with 30 mM lithium chloride. All embryos were fixed at indicated stages and hybridized with Fz5/8 antisense probe. HB, hatched blastula; MB, mesenchyme blastula; Pr, prism. Lateral views with the animal pole at the top.