Fig. 5. Skeletal muscle from Myogflox/flox and
Myogflox
/flox
mice at 10 weeks of age.
(A-D) Cross-sections (A,B) and longitudinal sections (C,D) of
hindlimbs. (E,F) Sections through tongues. (G-J) Sections
through diaphragms. One Myogflox
/flox
mouse
has a thin diaphragm (H). Thin diaphragms were found in only a single pair of
mice from a single litter. All other
Myogflox
/flox
mice had normal diaphragms
(J). Scale bar: 100 µm. (K) Identical myofiber diameters were
observed in Myogflox/flox and
Myogflox
/flox
mice. Myofiber diameters were
determined from cross-sections of hindlimbs of mice at 10 weeks of age. Each
column represents the diameters determined for individual myofibers from a
single hindlimb section (squares). The genotypes are shown below the
graph.