Development -- Mishra et al. 133 (4): 675 Figure IG4

(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.

Fig. 4. P2-receptor antagonists reduce the cytosolic Ca²⁺ elevations. Inhibitors (100 µM each) were applied 8 minutes prior to agonist application. The P2Y₁-receptor-specific antagonist MRS2179 reduced the Ca²⁺ signal evoked by ATP or ADP (50 µM each). The non-selective P2-receptor antagonists suramin or PPADS reduced the Ca²⁺ signals evoked by either ATP, ADP or UTP (mean±s.d., n=5-8, ^*P<0.05, ^**P<0.01).