Development -- Strickland et al. 133 (5): 823 Figure IG5

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Fig. 5. The basal lamina is disrupted surrounding Slit2^-/-;Ntn1^-/- EBs, but it is intact surrounding Slit2^-/- and Robo1^-/- EBs and all ducts. Immunostaining with anti-laminin 1 on EBs (A,C,E) and ducts (B,D,F). (A,B) Slit2^-/- EB and duct. (C,D) Robo1^-/- EB and duct. (E,F) Slit2^-/-;Ntn1^-/- EB and duct. Arrowheads indicate regions of intact basal lamina. Boxed region (E) indicates area where the basal lamina is disrupted. Scale bar: 20 µm.