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Figure 5


Fig. 5. Restricted diffusion of Shh can propagate a morphogen signal. (A) Extracellular Shh concentration and (B) intracellular Gli1 concentration are shown at t=83 hours at various Shh diffusivities. (C) The Gli1 protein interface position is shown at various diffusivities at t=83 hours. Simulation initial conditions and parameters are the same as those listed in Fig. 2, except DShh was varied.