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Figure 2


Fig. 2. Sequence analysis of hydkk1/2/4. (A) TCoffee alignment of HyDkk1/2/4 with the CRD2 of available Dkk molecules (see Materials and methods). (B) Domain structure of mouse Dkk4, NvDkk1/2/4 and HyDkk1/2/4; shaded boxes indicate conserved residues within CRD2; cysteines in red. (C) IQPNNI ML tree of Dkk CRD2 domains with TREE-PUZZLE support values (>50).