Fig. 5. Ft regulates PD wing growth and pattern. (A,B) Expression of
Dll (red) and Wg (green) in wild-type (A) and in ftfd
mutant (B) wing imaginal discs. Dll is upregulated in the ft mutant
discs (B). (C,C') In the posterior (P) wing compartment
displaying overexpression of Ft (UAS-ft/en-Gal4), Dll (red in C, grey
in C') is downregulated when compared with its anterior (A) compartment
or with that of a wild-type counterpart (also see
Fig. 8H); the broken line
(C') indicates the AP boundary. (D,D') A large
ft422 clone, marked by loss of GFP (green), displays
upregulated Q-vg-lacZ (red in D and grey in D'). (E) A
plot of the intensity of Q-vg-lacZ expression over the wing pouch
region (along the red broken line in D') to reveal upregulation of
Q-vg-lacZ in the mutant clone along the PD axis. (F,G) Adult
wing of a wild type (F) and of genotype en-Gal4/UAS-ft (G). Wing
growth along the PD axis in the posterior compartment is truncated (G), as
revealed by the close proximity of the anterior and posterior crossveins
(arrowheads); AP boundary is indicated by broken lines.