Fig. 6. ft genetically interacts with Wg signaling. (A) Expression of Arm^S10 (UAS-Arm^S10) under the regulation of the vg-Gal4 driver induces ectopic wing margin specific bristles in the wing blade. (B) This phenotype is enhanced by a reduction in the dose of ft (+/ft^fd). (C,D) Expression of a dominant-negative form of dTCF (UAS-dTCFN) under the vg-Gal4 driver induces loss of wing margin bristles (C); this phenotype is partly suppressed by a reduction in ft gene dose (d). (E-H') ß-Catenin/Arm levels (red or grey) respond to the levels of Ft. ft⁴²² mutant clones, marked by loss of GFP, display elevated levels of ß-catenin/Arm (E,E'). (F,F') Higher magnifications of some of these ft mutant clones (box in E) are displayed; insets show XZ projections through one such mutant clone to reveal upregulation of ß-catenin/Arm in ft mutant cells (non-GFP); broken line marks the clone border. Overexpression of Ft (en-Gal4/UAS-ft) (green, G-H') lowered the ß-catenin/Arm levels in the posterior (P) wing compartment compared with that of the anterior (A) wing compartment. (H,H') XZ section across the AP compartment of this disc (broken line in G,G') reveals downregulation of ß-catenin/Arm in the posterior (P) compartment.