Fig. 5. Restoration of proper synaptic architecture and BM composition in
skeletal muscle from Lamb2-/-; MCK-B2 mice.
(A,B) Colocalization of rat laminin ß2 (A) with
-bungarotoxin (B) in a highly ramified skeletal muscle synapse.
(C,D) Restoration of laminin
5 to synaptic BMs (C) identified by
-bungarotoxin (D). (E,F) Laminin ß1 (E, green in F) is not
associated with the
-bungarotoxin-positive synaptic clefts (red in the
merged image in F). Scale bar: 20 µm for A-F.