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Figure 3


Fig. 3. The Tbx1 conditional mutant phenotype. (A,B) Tbx1 conditional mutant phenotype at E11.5 (B) compared with a wild-type littermate (A). PAs are indicated with a dashed red line and denoted with arrows. PA, pharyngeal arch. (C,D) Coronal sections through the same embryos show a hypoplastic pharynx in the mutant (D) compared with the wild-type littermate (C). PEKO/-, Tbx1 flox/null; Foxg1-Cre/+; WT, wild type. Scale bars: 0.5 mm in A; 300 µm in C.