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Figure 4


Fig. 4. ISH with Fgf3 and Fgf8. (A-D) ISH with Fgf3 (A,B) and Fgf8 (C,D) probes at E10.0 reveals expression of both genes in the pharyngeal pouches (asterisks) of wild-type embryos (A,C). Conditional null embryos of the same stage (B,D) display a loss of both Fgf3 and Fgf8 in the pharyngeal pouches. OV, otic vesicle; PEKO/-, Tbx1 flox/null; Foxg1-Cre/+; WT, wild type. Scale bars: 0.1 mm.