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Figure 4


Fig. 4. C/EBP{alpha} regulates expression of surfactant proteins in vivo. Serial sections of lung from control and Cebpa{Delta}/{Delta} mice at E18.5 were stained for mature SP-B (A,B) and proSP-C (C,D). Staining for mature SP-B and proSP-C was markedly reduced in conducting airways and peripheral lung saccules in Cebpa{Delta}/{Delta} mice. Scale bar: 25 µm.